Will this work on a manual transmission Sedona?

No — this radiator is built for automatic transmission models only. Manual transmission Sedonas use a different core design without the transmission cooler circuit. Verify your transmission type before ordering.

Do I need to drain coolant before removing the old radiator?

Yes. Your cooling system will be under pressure when warm — allow the engine to cool completely, then open the drain plug at the bottom of the radiator or at the block to avoid spillage and burns.

What about the hoses and clamps — do I reuse the old ones?

Inspect your existing hoses for cracks, splits, or soft spots before reinstalling. If they're over five years old or show any wear, replacing them during the radiator swap prevents future leaks. Hoses and clamps are not included with this radiator.